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延边地区朝鲜族和汉族青少年不同类型肥胖与代谢综合征及其组分的相关性研究

作　者: 金银花
导　师: 方今女
学　校: 延边大学
专　业: 卫生毒理学
关键词: Adolescent Race Difierent type of obesity Metabolic Syndrome andits components Relationship
分类号: R589
类　型: 硕士论文
年　份: 2012年
下　载: 56次
引　用: 0次
阅　读: 论文下载

内容摘要

Objective To analyze the relationship between different types of obesity and metabolic syndrome (MS) and its components among Korean-Chinese and Han-Chinese adolescents in Yanbian area.Methods1) A total of1,207adolescents aged17～18years were finally selected in high school from Antu County of Yanbian and the survey were carried out in2008and2009. All of students knew the informed consent.2) Height, weight, waist circumference and blood pressure was measured by physical examination.3) Triglyceride (TG), high-density lipoprotein cholesterol (HDL-C) and blood glucose (FBG) were measured after12hour fasting.4) Body mass index (BMI, kg/m2), waist circumference (WC, cm) and waist-to-height ratio (WHtR) were employed as the obesity indices:overall obesity defined as BMI≥>P90,central obesity defined as WC≥>P90and WHtR≥0.46.5) MS was defined when any three of the five diagnostic criteria were present:①Central obesity defined as WC>P90;②Hypertension defined as SBP and (or) DBP>P90;③Low HDL cholesterol (low HDL-C) defined as HDL-C≤P10;④High triglyceride (high TG) defined as TG>P90;⑤Hyperglycemia defined as FBG≥P90.6) Continuous variables have been examined by t-test; the prevalence rates are given in percent and they have been examined by χ2test; the relationship between different types of obesity and metabolic syndrome (MS) and its components have been examined by Pearson and partial correlation analysis. Different types of obesity as the dependent variable and race, sex, hypertension, low HDL-C, high TG, Hyperglycemia, different type of obesity and MS as independent variables were analyzed by multivariate logistic regression analysis; the variables were selected by BACKWARD, selected variables were significant level as a=0.05and deleted variables were significant level as a=0.1.Results:1)The level of WC、WHtR、SBP、DBP、TG、FBG among Korean adolescents was significantly higher than among Han, and the level of HT and HDL-C in Korean was lower than in Han (P<0.01).2) The prevalence of central obesity(WC≥P90and WHtR≥0.46)(16.7%/9.1%and12.5%/5.9%), hypertension (36.8%/26.7%), high TG (37.5%/10.3%)and MS (8.3%/3.2%) in Korean was significantly higher than in Han (P<0.05).3)The level of WT, BMI, WC, WHtR, SBP, DBP, FBG(Han) in group with general obesity was higher than in normal group in both Korean and Han (P<0.05). The level of WT, BMI, WC, WHtR, SBP, DBP, FBG(Han) in group with central obesity (WC≥P90) was higher than in normal group in both Korean and Han (P<0.05). The level of HT (Han), WT, BMI, WC, WHtR, SBP, DBP, FBG (Han) in group with central obesity (WHtR≥0.46) was higher than in normal group in both Korean and Han (P<0.05).4) The prevalence of central obesity (WC≥P90and WHtR≥0.46), hypertension (Han), hyperglycemia (Han) and MS in group with general obesity was higher than in normal group in both Korean and Han (P<0.01). The prevalence of general obesity, central obesity (WHtR≥0.46), hypertension (Han), hyperglycemia and MS in group with central obesity (WC≥P9o) was higher than in normal group in both Korean and Han (P<0.05). The prevalence of general obesity, central obesity (WC≥P90), hypertension (Han), hyperglycemia (Han) and MS in group with central obesity (WHtR≥0.46) was higher than in normal group in both Korean and Han (P<0.05).5)There was a positive correlation between BMI and WHtR, WT, SBP, DBP, TG, FBG, and a negative correlation with HDL-C (P<0.01); there was a positive correlation between WC and BMI, WHtR, HT, WT, SBP, DBP, TG, FBG (P<0.05); there was a positive correlation between WHtR and BMI, WC, WT, SBP, DBP, TG, FBG, and a negative correlation with HT (P<0.01).6) The prevalence of hypertension, hyperglycemia and MS was obviously increased in the group of general obesity combined with central obesity (WHtR≥0.46), and that was higher than in the group with any one type of obesity (P<0.01). Central obesity seemed to be more effective to the risk of hyperglycemia and MS.7) Our multivariate logistic analysis showed that general obesity is closely related with hyperglycemia, hypertension, central obesity (WC≥P90and WHtR≥0.46) and MS; central obesity (WC≥P90) is closely related withhigh TG, hypertension, hyperglycemia general obesity and MS; central obesity (WHtR≥0.46) is closely related with race, sex, hypertension, hyperglycemia, general obesity and MS.Conclusion:1) The level of WC、WHtR、SBP、DBP、TG、FBG among Korean adolescents was significantly higher than among Han, and the level of HT and HDL-C in Korean was lower than in Han.2) The prevalence of central obesity (WC>P9o and WHtR>0.46), hypertension, high TG and MS in Korean was significantly higher than in Han.3) The level of HT, WT, BMI, WC, WHtR, SBP, DBP and FBG, and the prevalence of hypertension, hyperglycemia and MS in group with obesity was higher than in normal group.4) The prevalence of hypertension, hyperglycemia and MS was obviously increased in the group of general obesity combined with central obesity(WHtR>0.46). Central obesity seemed to be more effective to the risk of hyperglycemia and MS.5) Different types of obesity increased the risk of hypertension, hyperglycemia and MS. Combined use of BMI and WHtR can improve the prediction effect of hypertension, hyperglycemia and MS.

全文目录

Abstract  6-9
第一章前言  9-11
第二章对象与方法  11-13
  2.1 研究对象  11
  2.2 研究内容及方法  11
  2.3 统计分析  11-13
第三章结果  13-34
  3.1 不同民族学生一般体格及生化指标平均水平  13
  3.2 不同民族学生多代谢异常检出率  13
  3.3 不同类型肥胖学生体格及生化指标平均水  13-14
  3.4 不同类型肥胖学生多代谢异常的检出率  14-15
  3.5 BMI、WC、WHtR与体格及生化指标的相关关系  15-16
  3.6 BMI合并不同类型腹型肥胖对MS及其组分患病  16
  3.7 不同类型肥胖与各种影响因素的Logistic回归分析  16-34
第四章讨论  34-40
第五章结论  40-41
致谢  41-42
参考文献  42-50
综述  50-113
  参考文献  88-113
研究生期间发表学术论文及参与课题  113

延边地区朝鲜族和汉族青少年不同类型肥胖与代谢综合征及其组分的相关性研究

内容摘要

全文目录

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